Yes, I know, let’s not go there, shall we? MTHFR is the acronym for Methylenetetrahydrofolate reductase. It is a very common genetic deficiency (mutation simply sounds so decisive, as if nothing can be done to help alleviate the symptoms). Thankfully, there is help for this condition.


All of us have two of every gene. Sometimes, there is a SNP (pronounced snip) on one or both genes causing a deficiency. Someone with the MTHFR deficiency does not produce the enzyme methylenetetrahydrofolate reductase, which is responsible for eliminating toxins from the body, through a process called methylation. Some people with this condition have very serious symptoms and others go their whole lives unaware of the condition. This condition causes the inability of the body to hold onto B12 and B9.

Some of the health concerns from this deficiency are:

Venus Thrombosis.

Heart Disease.




Some practioner’s even suggest that

ADD/ADHD, Bi-Polar, Autism, Fibromyalgia, MS, among others, may be directly related to this genetic condition.

I am a researcher by nature so when a family member began to have some mental health concerns, I started researching. I came across information on MTHFR but wasn’t sure how to proceed and, unfortunately, it wasn’t until a full year and a half later that my family member was tested. I say unfortunately because this family member was subjected to too many harsh drugs over a long period of time that only exacerbated the situation making it worse than it should have been. There is a reason for this, as explained to us by our doctor. The neurological pathways in someone with this condition are stuck in the on or open position. When medication is introduced to help alleviate, for instance, anxiety or depression, it actual makes the situation worse. I can definitely attest to that. On the same token, if someone is experiencing anxiety or depression and is not receiving the right type and right amount of B12 and B9, they can exhibit signs of impulsivity, anger, erratic behavior, adiction, anxiety, depression and self -medicating.

If you or someone you know has any of these symptoms, I encourage you to do a genetic test, such as 23andme. Once you receive the link that your data is available, you can link it to a free service, like genetic genie and it will give you the information about any deficiency in relation to MTHFR, the methylation cycle and liver detox.

Once you have this information you can take it to a doctor that understands what MTHFR is all about and come up with a supplement protocol that works best for you. You may have to find a naturopathic, osteopathic or functional medical doctor because not many doctors understand the condition at the present time. Please don’t get discouraged they are out there and you may have to pay out of pocket but it is worth it to feel better. To enjoy living in your skin again! Also, what works for one person may not work for you. For example, what works for my loved one definitely does not work for me.

Get tested, find a knowledgeable doctor and work with him/her on a supplement protocol.

As for my loved one, completely off medication and enjoying life again!





Author: Terese

Terese is a wife, mother, Grammie, sister, aunt and friend. Best of all a daughter of the King! Terese is a Bible study teacher and speaker. One of her passions is investing in the lives of other women and encouraging them in their identity and authority in Christ. Terese is a life long student of God's grace.

One thought on “MTHFR…What?!!”

Find your voice and let yourself be heard! Please leave any insight and thoughts in the comment section.

This site uses Akismet to reduce spam. Learn how your comment data is processed.